Flight Connections to Tajikistan and Kyrgyzstan
New York City to Dushanbe with only one stop in Istanbul.
Also from South America you can fly e.g. from Buenos Aires via San Paolo and Istanbul to Dushanbe (return: from 1300$)
New York City to Bishkek (return) starting from 650$): Continue then with local airlines or public transport to Osh and come to the Pamirs!
Daily flights from several european cities via Istanbul to Dushanbe and Osh (Kyrgyzstan)
Daily flights from several European cities via Almaty or Astana to Dushanbe
Weekly non-stop flights from Frankfurt (M) to Dushanbe.
Daily flights from several European Cities via Moscow to Osh, Khujand, Kulob and Dushanbe. Khunjand-Berlin currently 190$
Very cheap flights from different European cities to Bishkek (Kyrgyzstan) (for example Berlin, Dusseldorf & Paris)
And from Bishkek you can continue with Pegasus Airlines partner, Air Manas to Osh (up to 5 flights daily, flight time: 40 minutes)
Daily flights from several Asian cities (Kuala Lumpur, Abu Dhabi) via Almaty or Astana to Dushanbe
Several weekly flights from Dubai to Dushanbe
Weekly flights from Tehran and Delhi to Dushanbe
Daily flights from Tokyo and other Asian cities via Istanbul to Dushanbe
Connects east Asian cities via Ürumqi to Dushanbe.